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Purified Bee Venom

Purified Bee Venom

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What is bee venom?

  • Bee venom is a clean and clear aromatic liquid with a bitter taste, which dries quickly at room temperature. After evaporation, 30%–40% of it remains as crystal (refer to the picture).
  • Dried bee venom is thermostable, so it does not lose its characteristics even when heated at 100°C, but it can be destroyed by oxidizing materials.

Table 1. Pharmacological Actions and Substances of Bee Venom

Substance Pharmacological Action Dry Weight (%) Molecular Weight (kD)
Melittin Cell-dissolving action 40-50 2.8
Apamin Neuralgia relief, pain relief, anti-inflammatory effect, immunization, and neurotoxic effect 2-3 2.02
MCD-Peptide 401 Anti-inflammatory effect 2-3 2.6
Adolapin Anti-inflammatory effect, pain relief, and fever alleviation effect 0.5-1 11.5
Protease inhibitor Inhibition of dissolving protein and ester, and anti-inflammatory action 0.1-0.8 9.0
Secapine Hypothermia relief 0.5-2 2
Procamine A, B Radiation protection 1-2 0.4
Hyaluronidase Tissue breakdown and antigenic substance 1 38
Phospholipase A2 Cell tissue breakdown and hemolytic and catalytic actions 10-13 19
Histamine Blood pressure reduction, intestinal contraction, and enhanced stomach acid secretion 0.5-2 0.12
Dopamine Neurotransmitter 0.2-1 0.15

Necessity of bee venom

  • Made from pure natural materials
  • Strong antibacterial, anti-inflammatory, and immune-enhancing effects
  • Low risk of adverse effects and residues
  • Used for treating various diseases in oriental medicine for a long time